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USMLE Toxoplasmosis (TORCH infection)

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What Is Toxoplasmosis? Symptoms And Treatment | familydoctor.org[1]

Etiology: Toxoplasma gondii 

Risk Category: Pregnant women; debilitated patients. If HIV positive CD4 count less than 100

Mode of Transmission: 
     1) Oocysts in cat feces
     2) Contaminated meat having oocysts 
     3) Through placenta (if mother acquires Toxoplasmosis during pregnancy) 

Imaging: (CT/MRI)  
     Ring enhancing lesion 

Triad: 
     1) Intracranial calcification (Dystrophic calcification) 
     2) Hydrocephalous 
     3) Chorioretinitis 

Treatment: 
     Sulfadiazine plus Pyrimethamine 

Prophylaxis in AIDS patient: 
   Trimethoprim and Sulfamethoxazole 

References: 
[1] https://familydoctor.org/condition/toxoplasmosis/ [Online] / auth. familydoctor.org //      https://familydoctor.org.

 




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